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CAS 129938-20-1 Dapoxetine


Title:
CAS 129938-20-1 Dapoxetine
Type:
Sell
Listing Began:
Mon, 08 Jan 2018 15:30:19 +0800
Duration:
1095 Days
Price:
Price Negotiable.
Description:
Email:Fredeboo@chembj.com
Skype:fredeboo_2
Whatsapp:+86 18038709085

Alias: Priligy,Dapoxetine hydrochloride,Dapoxe, Dapoxeti ,Dapoxetinehy, Dapoxetine hydrochloride
CAS No: 129938-20-1 or 119356-77-3
Molecular Formula:C21H24ClNO
Molecular weight:341.88
Purity: 98%
Appearance: White crystalline powder
Solubility:soluble in water and alcohol.
Usage: Can be used as pharmaceutical material , Dapoxetine improves erectile function significantly, possibly increase testosterone through increased sexual activity, and it is very safe.

Dapoxetine, marketed as Priligy (among and other brands) is the first compound developed specially for the treatment of premature ejaculation (PE) for men between18-64 years old. Dapoxetine works by inhibiting the serotonin transporter, increasing serotonin’s action at the post synaptic cleft, so as to delay consequence ejaculation. As a member of selective serotonin reuptake inhibitor (SSRI) family, Dapoxetine was initially created as an antidepressant. However, unlike other SSRIs, Dapoxetine is absorbed and eliminated rapidly in the body. Its immediate response makes it suitable for the treatment of PE but not as an antidepressant.

Treat male premature ejaculation and erectile dysfunction.
Due to the lack of specific approval treatment for PE in the US and some other countries, other SSRIs such as Fluoxetine, Paroxetine, Sertraline, Fluvoxamine, and Citalopram have been used as clinical drugs to treat PE. Waldinger’s meta analysis shows that the use of these conventional antidepressants increasing IELT about 2-9 time in comparison of three to eight times when Dapoxetine is used. However, these SSRIs must be taken daily in order to achieve meaningful efficacy, and the long half-life increases the risk of the drug accumulation and as a consequence, an increasing adverse effects such as decreasing sexual libido and causing erectile dysfunction. Dapoxetine, on the other hand, is a fast-acting SSRI. It is rapidly absorbed and eliminated from the body within a few hours. This favorable pharmacokinetics minimizes the risk of the drug’s accumulation in the body, and therefore reducing side effects.


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